CCMC Health System announces the results of a four-years long study on the efficacy of a novel treatment intervention, the Physiologic Insulin Resensitization (PIR) Program, which aims to reduce cellular insulin resistance and improve chronic disease conditions. The physician directed IV infusion treatment is precision insulin dosing over time. It is provided in an outpatient clinic setting to eligible patients with chronic disease including diabetes.

CCMC Health System’s study of its largely rural patient base shows documented improvement in increasing kidney filtration rates in 165 patients as measured by their GFR (Glomerular Filtration Rate) tests. The Physiologic Insulin Resensitization Program even helped reverse chronic kidney disease (GKD) in patients with end-stage renal disease (Stage 5), some of whom were on dialysis.

Kidney disease is a common and costly medical condition suffered by many millions of people. It affects the kidney’s ability to filter waste and fluid in the blood. Most common is CKD which progresses over time causing high blood pressure and other conditions. Nearly one in seven adults in the U.S. are reported to have CKD, many don’t know they have it, and one in three with diabetes also suffer from it.

Improving kidney filtration (increasing GFR measures) means the organ is working better to remove waste and excess water from blood in the body. In so doing, the body is better able to maintain a healthier balance of salts and minerals and produce needed hormones and red blood cells.

Dr. Larry G. Troxell, Chief Executive Officer, who leads the CCMC study says “Our aim is to reduce chronic disease and improve quality of life for patients, and we’ve seen remarkable outcomes with the Physiologic Insulin Resensitization (PIR) intervention. Patients were already seeing restored energy, a reduction in obesity, and the need for certain medications. Now, this study shows a breakthrough – PIR is working to help reverse kidney disease. We’re helping reduce a major health problem for our patients in Texas which could herald improved health for people across the U.S.”

Troxell has been on the forefront of adopting PIR as an effective intervention based on scientific research done nationally and the findings in the CCMC study. He added, “In addition to PIR success, there’s a new CPT infusion billing code issued by Centers for Medicare & Medicaid Services (CMS) that’s making the claims process more efficient for patients and providers.”